Peptide amphiphile delivery of sonic hedgehog protein promotes neurite formation in penile projecting neurons

Erectile dysfunction (ED) critically impacts quality of life in prostatectomy, diabetic and aging patients. The underlying mechanism involves cavernous nerve (CN) damage, resulting in ED in 80% of prostatectomy patients. Peptide amphiphile (PA) nanofiber hydrogel delivery of sonic hedgehog (SHH) pro...

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Vydáno v:Nanomedicine
Hlavní autoři: Dobbs, Ryan, Choe, Shawn, Kalmanek, Elizabeth, Harrington, Daniel A., Stupp, Samuel I., McVary, Kevin T., Podlasek, Carol A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241323/
https://ncbi.nlm.nih.gov/pubmed/30037776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2018.06.006
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