AB300. SPR-27 Sonic hedgehog promotes sprouting of neurons in the pelvic ganglia and cavernous nerve during regeneration

OBJECTIVE: We’ve shown in previous studies that sonic hedgehog (SHH) protein delivered by nanoparticle based peptide amphiphile (PA) hydrogels to the cavernous nerve (CN) at the time of crush injury (mimicking prostatectomy), are neuroprotective and promote CN regeneration in a rat model. The mechan...

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Publicado no:Transl Androl Urol
Main Authors: Dobbs, Ryan, Choe, Shawn, Harrington, Daniel A., Stupp, Samuel I., McVary, Kevin T., Podlasek, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2016
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Abstract
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5143243/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tau.2016.s300
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