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PLIN2 Is Essential for Trophoblastic Lipid Droplet Accumulation and Cell Survival During Hypoxia

Trophoblast hypoxia and injury, key components of placental dysfunction, are associated with fetal growth restriction and other complications of pregnancy. Accumulation of lipid droplets has been found in hypoxic nonplacental cells. Unique to pregnancy, lipid accumulation in the placenta might pertu...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Bildirici, Ibrahim, Schaiff, W Timothy, Chen, Baosheng, Morizane, Mayumi, Oh, Soo-Young, O’Brien, Matthew, Sonnenberg-Hirche, Christina, Chu, Tianjiao, Barak, Yaacov, Nelson, D Michael, Sadovsky, Yoel
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240902/
https://ncbi.nlm.nih.gov/pubmed/30351430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00752
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