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Pif1 helicase unfolding of G-quadruplex DNA is highly dependent on sequence and reaction conditions

In addition to unwinding double-stranded nucleic acids, helicase activity can also unfold noncanonical structures such as G-quadruplexes. We previously characterized Pif1 helicase catalyzed unfolding of parallel G-quadruplex DNA. Here we characterized unfolding of the telomeric G-quadruplex, which c...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Byrd, Alicia K., Bell, Matthew R., Raney, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240867/
https://ncbi.nlm.nih.gov/pubmed/30257865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004499
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