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Insertion sequence 1 from calpain-3 is functional in calpain-2 as an internal propeptide
Calpains are intracellular, calcium-activated cysteine proteases. Calpain-3 is abundant in skeletal muscle, where its mutation-induced loss of function causes limb-girdle muscular dystrophy type 2A. Unlike the small subunit–containing calpain-1 and -2, the calpain-3 isoform homodimerizes through pai...
Enregistré dans:
| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240860/ https://ncbi.nlm.nih.gov/pubmed/30254072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004803 |
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