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Absolute Binding Free Energies for the SAMPL6 Cucurbit[8]uril Host-Guest Challenge via the AMOEBA Polarizable Force Field

As part of the SAMPL6 host-guest blind challenge, the AMOEBA force field was applied to calculate the absolute binding free energy for a cucurbit[8]uril host complexed with 14 diverse guests, ranging from small, rigid structures to drug molecules. The AMOEBA results from the initial submission promp...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Comput Aided Mol Des
Egile Nagusiak: Laury, Marie L., Wang, Zhi, Gordon, Aaron S., Ponder, Jay W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240481/
https://ncbi.nlm.nih.gov/pubmed/30324303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-018-0147-5
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