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Calculating binding free energies of host-guest systems using AMOEBA polarizable force field

Molecular recognition is of paramount interest in many applications. Here we investigate a series of host-guest systems previously used in the SAMPL4 blind challenge by using molecular simualtions and the AMOEBA polarizable force field. The free energy results computed by Bennett’s acceptance ratio...

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Detalhes bibliográficos
Publicado no:Phys Chem Chem Phys
Main Authors: Bell, David R., Qi, Rui, Jing, Zhifeng, Xiang, Jin Yu, Mejias, Christopher, Schnieders, Michael J., Ponder, Jay W., Ren, Pengyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102783/
https://ncbi.nlm.nih.gov/pubmed/27254477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cp02509a
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