Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora Disease

Lafora disease (LD), the most devastating adolescence-onset epilepsy, is caused by mutations in the EPM2A or EPM2B genes, which encode the proteins laforin and malin, respectively. Loss of function of one of these proteins, which are involved in the regulation of glycogen synthesis, induces the accu...

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Bibliografiske detaljer
Udgivet i:Glia
Main Authors: Augé, Elisabet, Pelegrí, Carme, Manich, Gemma, Cabezón, Itsaso, Guinovart, Joan J., Duran, Jordi, Vilaplana, Jordi
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240358/
https://ncbi.nlm.nih.gov/pubmed/30152044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23463
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