ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition

BACKGROUND: Epithelial mesenchymal transition (EMT) is tightly regulated by a network of transcription factors (EMT-TFs). Among them is the nuclear factor ZEB2, a member of the zinc-finger E-box binding homeobox family. ZEB2 nuclear localization has been identified in several cancer types, and its o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Epigenetics Chromatin
Hauptverfasser: Skrypek, Nicolas, Bruneel, Kenneth, Vandewalle, Cindy, De Smedt, Eva, Soen, Bieke, Loret, Nele, Taminau, Joachim, Goossens, Steven, Vandamme, Niels, Berx, Geert
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240308/
https://ncbi.nlm.nih.gov/pubmed/30445998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0239-4
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