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ADP-Ribosylation Factor-Like 2 (ARL2) regulates cilia stability and development of outer segments in rod photoreceptor neurons

Photoreceptor cells are specialized neurons with a sensory cilium carrying an elaborate membrane structure, the outer segment (OS). Inherited mutations in genes involved in ciliogenesis frequently result in OS malformation and blindness. ADP-ribosylation factor-like 2 (ARL2) has recently been implic...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Wright, Zachary C., Loskutov, Yuriy, Murphy, Daniel, Stoilov, Peter, Pugacheva, Elena, Goldberg, Andrew F. X., Ramamurthy, Visvanathan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240099/
https://ncbi.nlm.nih.gov/pubmed/30446707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35395-3
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