Evidence of Polygenic Adaptation to High Altitude from Tibetan and Sherpa Genomes

Although Tibetans and Sherpa present several physiological adjustments evolved to cope with selective pressures imposed by the high-altitude environment, especially hypobaric hypoxia, few selective sweeps at a limited number of hypoxia related genes were confirmed by multiple genomic studies. Nevert...

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Detalhes bibliográficos
Publicado no:Genome Biol Evol
Main Authors: Gnecchi-Ruscone, Guido A, Abondio, Paolo, De Fanti, Sara, Sarno, Stefania, Sherpa, Mingma G, Sherpa, Phurba T, Marinelli, Giorgio, Natali, Luca, Di Marcello, Marco, Peluzzi, Davide, Luiselli, Donata, Pettener, Davide, Sazzini, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239493/
https://ncbi.nlm.nih.gov/pubmed/30335146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy233
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