Reconstitution of mammalian cleavage factor II involved in 3′ processing of mRNA precursors

Cleavage factor II (CF II) is a poorly characterized component of the multiprotein complex catalyzing 3′ cleavage and polyadenylation of mammalian mRNA precursors. We have reconstituted CF II as a heterodimer of hPcf11 and hClp1. The heterodimer is active in partially reconstituted cleavage reaction...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Schäfer, Peter, Tüting, Christian, Schönemann, Lars, Kühn, Uwe, Treiber, Thomas, Treiber, Nora, Ihling, Christian, Graber, Anne, Keller, Walter, Meister, Gunter, Sinz, Andrea, Wahle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6239180/
https://ncbi.nlm.nih.gov/pubmed/30139799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.068056.118
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