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Panel sequencing of 264 candidate susceptibility genes and segregation analysis in a cohort of non-BRCA1, non-BRCA2 breast cancer families

PURPOSE: The main aim of this study was to screen epigenetic modifier genes and known breast cancer driver genes for germline mutations in non-BRCA1/2 (BRCAx) breast cancer families in order to identify novel susceptibility genes of moderate-high penetrance. METHODS: We screened 264 candidate suscep...

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Dettagli Bibliografici
Pubblicato in:Breast Cancer Res Treat
Autori principali: Li, Jun, Li, Hongyan, Makunin, Igor, Investigators, kConFab, Thompson, Bryony A., Tao, Kayoko, Young, Erin L., Lopez, Jacqueline, Camp, Nicola J., Tavtigian, Sean V., John, Esther M., Andrulis, Irene L., Khanna, Kum Kum, Goldgar, David, Chenevix-Trench, Georgia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238949/
https://ncbi.nlm.nih.gov/pubmed/28840378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4469-0
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