A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis

Asthma is one of the most common immunological diseases and is characterized by airway hyperresponsiveness (AHR), mucus overproduction, and airway eosinophilia. Although mouse models have provided insight into the mechanisms by which type-2 cytokines induce asthmatic airway inflammation, differences...

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Bibliografski detalji
Izdano u:JCI Insight
Glavni autori: Ito, Ryoji, Maruoka, Shuichiro, Soda, Kaori, Katano, Ikumi, Kawai, Kenji, Yagoto, Mika, Hanazawa, Asami, Takahashi, Takeshi, Ogura, Tomoyuki, Goto, Motohito, Takahashi, Riichi, Toyoshima, Shota, Okayama, Yoshimichi, Izuhara, Kenji, Gon, Yasuhiro, Hashimoto, Shu, Ito, Mamoru, Nunomura, Satoshi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238753/
https://ncbi.nlm.nih.gov/pubmed/30385714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121580
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