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A humanized mouse model to study asthmatic airway inflammation via the human IL-33/IL-13 axis

Asthma is one of the most common immunological diseases and is characterized by airway hyperresponsiveness (AHR), mucus overproduction, and airway eosinophilia. Although mouse models have provided insight into the mechanisms by which type-2 cytokines induce asthmatic airway inflammation, differences...

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Библиографические подробности
Опубликовано в: :JCI Insight
Главные авторы: Ito, Ryoji, Maruoka, Shuichiro, Soda, Kaori, Katano, Ikumi, Kawai, Kenji, Yagoto, Mika, Hanazawa, Asami, Takahashi, Takeshi, Ogura, Tomoyuki, Goto, Motohito, Takahashi, Riichi, Toyoshima, Shota, Okayama, Yoshimichi, Izuhara, Kenji, Gon, Yasuhiro, Hashimoto, Shu, Ito, Mamoru, Nunomura, Satoshi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238753/
https://ncbi.nlm.nih.gov/pubmed/30385714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121580
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