CYP2B6 Genetic Polymorphisms, Depression, and Viral Suppression in Adults Living with HIV Initiating Efavirenz-Containing Antiretroviral Therapy Regimens in Uganda: Pooled Analysis of Two Prospective Studies

Single-nucleotide polymorphisms (SNPs) in CYP2B6 have been shown to predict variation in plasma efavirenz concentrations, but associations between these SNPs and efavirenz-mediated depression and viral suppression are less well described. We evaluated three SNPs in CYP2B6 (rs3745274, rs28399499, and...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Chang, Jonathan L., Lee, Sulggi A., Tsai, Alexander C., Musinguzi, Nicholas, Muzoora, Conrad, Bwana, Bosco, Boum, Yap, Haberer, Jessica E., Hunt, Peter W., Martin, Jeff, Bangsberg, David R., Kroetz, Deanna L., Siedner, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2018
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238612/
https://ncbi.nlm.nih.gov/pubmed/29973058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2018.0062
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