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Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

Myeloid-derived suppressor cells (MDSCs) inhibit anti-tumor immunity. Aerobic glycolysis is a hallmark of cancer. However, the link between MDSCs and glycolysis is unknown in patients with triple-negative breast cancer (TNBC). Here, we detect abundant glycolytic activities in human TNBC. In two TNBC...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Li, Wei, Tanikawa, Takashi, Kryczek, Ilona, Xia, Houjun, Li, Gaopeng, Wu, Ke, Wei, Shuang, Zhao, Lili, Vatan, Linda, Wen, Bo, Shu, Pan, Sun, Duxin, Kleer, Celina, Wicha, Max, Sabel, Michael, Tao, Kaixiong, Wang, Guobin, Zou, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238219/
https://ncbi.nlm.nih.gov/pubmed/29805099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.04.022
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