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Myeloid-derived suppressor cells endow stem-like qualities to breast cancer cells through IL-6/STAT3 and NO/NOTCH cross-talk signaling

Myeloid-derived suppressor cells (MDSC) contribute to immune suppression in cancer, but the mechanisms through which they drive metastatic progression are not fully understood. In this study, we show how MDSC convey stem-like qualities to breast cancer cells that coordinately help enable immune supp...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Peng, Dongjun, Tanikawa, Takashi, Li, Wei, Zhao, Lili, Vatan, Linda, Szeliga, Wojciech, Wan, Shanshan, Wei, Shuang, Wang, Yin, Liu, Yan, Staroslawska, Elzbieta, Szubstarski, Franciszek, Rolinski, Jacek, Grywalska, Ewelina, Stanisławek, Andrzej, Polkowski, Wojciech, Kurylcio, Andrzej, Kleer, Celina, Chang, Alfred E., Wicha, Max, Sabel, Michael, Zou, Weiping, Kryczek, Ilona
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891237/
https://ncbi.nlm.nih.gov/pubmed/27197152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2528
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