Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol

An enhanced stability of enzymes in organic solvents is desirable under industrial conditions. The potential of lipases as biocatalysts is mainly limited by their denaturation in polar alcohols. In this study, we focused on selected solvent tunnels in lipase from Geobacillus stearothermophilus T6 to...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Gihaz, Shalev, Kanteev, Margarita, Pazy, Yael, Fishman, Ayelet
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Enzymology and Protein Engineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6238069/
https://ncbi.nlm.nih.gov/pubmed/30217852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02143-18
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