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Protein Engineering by Random Mutagenesis and Structure-Guided Consensus of Geobacillus stearothermophilus Lipase T6 for Enhanced Stability in Methanol

The abilities of enzymes to catalyze reactions in nonnatural environments of organic solvents have opened new opportunities for enzyme-based industrial processes. However, the main drawback of such processes is that most enzymes have a limited stability in polar organic solvents. In this study, we e...

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Autores principales: Dror, Adi, Shemesh, Einav, Dayan, Natali, Fishman, Ayelet
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911059/
https://ncbi.nlm.nih.gov/pubmed/24362426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03371-13
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