A Systematic Review on Novel Mycobacterium tuberculosis Antigens and Their Discriminatory Potential for the Diagnosis of Latent and Active Tuberculosis

Background: Current immunodiagnostic tests for tuberculosis (TB) are based on the detection of an immune response toward mycobacterial antigens injected into the skin or following an in-vitro simulation in interferon gamma-release assays. Both tests have limited sensitivity and are unable to differe...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Meier, Noëmi R., Jacobsen, Marc, Ottenhoff, Tom H. M., Ritz, Nicole
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237970/
https://ncbi.nlm.nih.gov/pubmed/30473692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02476
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