Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection.

BACKGROUND: T-cell responses against dormancy-, resuscitation-, and reactivation-associated antigens of Mycobacterium tuberculosis are candidate biomarkers of latent infection in humans. METHODOLOGY/PRINCIPAL FINDINGS: We established an assay based on two rounds of in vitro restimulation and intrace...

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Auteurs principaux: Sebastian D Schuck, Henrik Mueller, Frank Kunitz, Albert Neher, Harald Hoffmann, Kees L C M Franken, Dirk Repsilber, Tom H M Ottenhoff, Stefan H E Kaufmann, Marc Jacobsen
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2009-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC2680040?pdf=render
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