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The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain

The homeostasis of the proteome depends on the tight regulation of the mRNA and protein abundances, of the translation rates, and of the protein lifetimes. Results from several studies on prokaryotes or eukaryotic cell cultures have suggested that protein homeostasis is connected to, and perhaps reg...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mandad, Sunit, Rahman, Raza-Ur, Centeno, Tonatiuh Pena, Vidal, Ramon O., Wildhagen, Hanna, Rammner, Burkhard, Keihani, Sarva, Opazo, Felipe, Urban, Inga, Ischebeck, Till, Kirli, Koray, Benito, Eva, Fischer, André, Yousefi, Roya Y., Dennerlein, Sven, Rehling, Peter, Feussner, Ivo, Urlaub, Henning, Bonn, Stefan, Rizzoli, Silvio O., Fornasiero, Eugenio F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237891/
https://ncbi.nlm.nih.gov/pubmed/30443017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35277-8
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