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Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells

Afadin is a cytoplasmic protein of the adherens junctions, which regulates the formation and stabilization of both the adherens and the tight junctions. Aberrant expression of Afadin has been shown in cancer and its loss has been associated with epithelial-to-mesenchymal transition (EMT). EMT is cha...

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Marques, Miguel Sardinha, Melo, Joana, Cavadas, Bruno, Mendes, Nuno, Pereira, Luísa, Carneiro, Fátima, Figueiredo, Ceu, Leite, Marina
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237830/
https://ncbi.nlm.nih.gov/pubmed/30473688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02712
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