Afadin Downregulation by Helicobacter pylori Induces Epithelial to Mesenchymal Transition in Gastric Cells

Afadin is a cytoplasmic protein of the adherens junctions, which regulates the formation and stabilization of both the adherens and the tight junctions. Aberrant expression of Afadin has been shown in cancer and its loss has been associated with epithelial-to-mesenchymal transition (EMT). EMT is cha...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Marques, Miguel Sardinha, Melo, Joana, Cavadas, Bruno, Mendes, Nuno, Pereira, Luísa, Carneiro, Fátima, Figueiredo, Ceu, Leite, Marina
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237830/
https://ncbi.nlm.nih.gov/pubmed/30473688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02712
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