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Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity
Retroviruses package two complete RNA genomes into a viral particle but generate only one provirus after each infection. This pseudodiploid replication strategy facilitates frequent recombination, which occurs during DNA synthesis when reverse transcriptase switches templates between two copackaged...
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| 發表在: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237782/ https://ncbi.nlm.nih.gov/pubmed/30307534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky910 |
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