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High-affinity RNA targets of the Survival Motor Neuron protein reveal diverse preferences for sequence and structural motifs
The Survival Motor Neuron (SMN) protein is essential for survival of all animal cells. SMN harbors a nucleic acid-binding domain and plays an important role in RNA metabolism. However, the RNA-binding property of SMN is poorly understood. Here we employ iterative in vitro selection and chemical stru...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237763/ https://ncbi.nlm.nih.gov/pubmed/30165668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky770 |
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