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A Multilayered Control of the Human Survival Motor Neuron Gene Expression by Alu Elements

Humans carry two nearly identical copies of Survival Motor Neuron gene: SMN1 and SMN2. Mutations or deletions of SMN1, which codes for SMN, cause spinal muscular atrophy (SMA), a leading genetic disease associated with infant mortality. Aberrant expression or localization of SMN has been also implic...

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Detaylı Bibliyografya
Yayımlandı:Front Microbiol
Asıl Yazarlar: Ottesen, Eric W., Seo, Joonbae, Singh, Natalia N., Singh, Ravindra N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5694776/
https://ncbi.nlm.nih.gov/pubmed/29187847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02252
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