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A Multilayered Control of the Human Survival Motor Neuron Gene Expression by Alu Elements
Humans carry two nearly identical copies of Survival Motor Neuron gene: SMN1 and SMN2. Mutations or deletions of SMN1, which codes for SMN, cause spinal muscular atrophy (SMA), a leading genetic disease associated with infant mortality. Aberrant expression or localization of SMN has been also implic...
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| Publié dans: | Front Microbiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5694776/ https://ncbi.nlm.nih.gov/pubmed/29187847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02252 |
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