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Active site flexibility revealed in crystal structures of Parabacteroides merdae β‐glucuronidase from the human gut microbiome

β‐Glucuronidase (GUS) enzymes in the gastrointestinal tract are involved in maintaining mammalian‐microbial symbiosis and can play key roles in drug efficacy and toxicity. Parabacteroides merdae GUS was identified as an abundant mini‐Loop 2 (mL2) type GUS enzyme in the Human Microbiome Project gut m...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Little, Michael S., Ervin, Samantha M., Walton, William G., Tripathy, Ashutosh, Xu, Yongmei, Liu, Jian, Redinbo, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237702/
https://ncbi.nlm.nih.gov/pubmed/30230652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3507
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