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Active site flexibility revealed in crystal structures of Parabacteroides merdae β‐glucuronidase from the human gut microbiome

β‐Glucuronidase (GUS) enzymes in the gastrointestinal tract are involved in maintaining mammalian‐microbial symbiosis and can play key roles in drug efficacy and toxicity. Parabacteroides merdae GUS was identified as an abundant mini‐Loop 2 (mL2) type GUS enzyme in the Human Microbiome Project gut m...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Little, Michael S., Ervin, Samantha M., Walton, William G., Tripathy, Ashutosh, Xu, Yongmei, Liu, Jian, Redinbo, Matthew R.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237702/
https://ncbi.nlm.nih.gov/pubmed/30230652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3507
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