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Active site flexibility revealed in crystal structures of Parabacteroides merdae β‐glucuronidase from the human gut microbiome

β‐Glucuronidase (GUS) enzymes in the gastrointestinal tract are involved in maintaining mammalian‐microbial symbiosis and can play key roles in drug efficacy and toxicity. Parabacteroides merdae GUS was identified as an abundant mini‐Loop 2 (mL2) type GUS enzyme in the Human Microbiome Project gut m...

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Bibliografski detalji
Izdano u:Protein Sci
Glavni autori: Little, Michael S., Ervin, Samantha M., Walton, William G., Tripathy, Ashutosh, Xu, Yongmei, Liu, Jian, Redinbo, Matthew R.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237702/
https://ncbi.nlm.nih.gov/pubmed/30230652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3507
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