Palmitic acid induces human osteoblast-like Saos-2 cell apoptosis via endoplasmic reticulum stress and autophagy

Palmitic acid (PA) is the most common saturated long-chain fatty acid in food that causes cell apoptosis. However, little is known about the molecular mechanisms of PA toxicity. In this study, we explore the effects of PA on proliferation and apoptosis in human osteoblast-like Saos-2 cells and uncov...

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Dettagli Bibliografici
Pubblicato in:Cell Stress Chaperones
Autori principali: Yang, Lei, Guan, Gaopeng, Lei, Lanjie, Lv, Qizhuang, Liu, Shengyuan, Zhan, Xiuwen, Jiang, Zhenzhen, Gu, Xiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2018
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237680/
https://ncbi.nlm.nih.gov/pubmed/30194633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-018-0936-8
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