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Palmitic acid induces human osteoblast-like Saos-2 cell apoptosis via endoplasmic reticulum stress and autophagy

Palmitic acid (PA) is the most common saturated long-chain fatty acid in food that causes cell apoptosis. However, little is known about the molecular mechanisms of PA toxicity. In this study, we explore the effects of PA on proliferation and apoptosis in human osteoblast-like Saos-2 cells and uncov...

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Библиографические подробности
Опубликовано в: :Cell Stress Chaperones
Главные авторы: Yang, Lei, Guan, Gaopeng, Lei, Lanjie, Lv, Qizhuang, Liu, Shengyuan, Zhan, Xiuwen, Jiang, Zhenzhen, Gu, Xiang
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Netherlands 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237680/
https://ncbi.nlm.nih.gov/pubmed/30194633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-018-0936-8
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