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Immunological changes with kinase inhibitor therapy for chronic lymphocytic leukemia

Ibrutinib and idelalisib are kinase inhibitors that have revolutionized the treatment of chronic lymphocytic leukemia (CLL). Capable of inducing durable remissions, these agents also modulate the immune system. Both ibrutinib and idelalisib abrogate the tumor-supporting microenvironment by disruptin...

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Publicat a:Leuk Lymphoma
Autors principals: Pleyer, Christopher, Wiestner, Adrian, Sun, Clare
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237652/
https://ncbi.nlm.nih.gov/pubmed/29764250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2018.1457147
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