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Immunological changes with kinase inhibitor therapy for chronic lymphocytic leukemia

Ibrutinib and idelalisib are kinase inhibitors that have revolutionized the treatment of chronic lymphocytic leukemia (CLL). Capable of inducing durable remissions, these agents also modulate the immune system. Both ibrutinib and idelalisib abrogate the tumor-supporting microenvironment by disruptin...

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Publicado en:Leuk Lymphoma
Main Authors: Pleyer, Christopher, Wiestner, Adrian, Sun, Clare
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237652/
https://ncbi.nlm.nih.gov/pubmed/29764250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2018.1457147
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