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An alternative renin isoform is cardioprotective by modulating mitochondrial metabolism
The renin‐angiotensin system promotes oxidative stress, apoptosis, necrosis, fibrosis, and thus heart failure. Secretory renin plays a central role in these processes, initiating the generation of angiotensins. Nevertheless, alternative renin transcripts exist, which code for a cytosolically localiz...
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| Publicado no: | J Cell Mol Med |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237583/ https://ncbi.nlm.nih.gov/pubmed/30247805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13872 |
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