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Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS
Neuroinflammation is a recognized pathogenic mechanism underlying motor neuron degeneration in amyotrophic lateral sclerosis (ALS), but the inflammatory mechanisms influencing peripheral motor axon degeneration remain largely unknown. A recent report showed a pathogenic role for c-Kit–expressing mas...
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| Publié dans: | JCI Insight |
|---|---|
| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237484/ https://ncbi.nlm.nih.gov/pubmed/30282815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123249 |
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