Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injury

Macrophages polarize into heterogeneous proinflammatory M1 and antiinflammatory M2 subtypes. Heme oxygenase 1 (HO-1) protects against inflammatory processes such as ischemia-reperfusion injury (IRI), organ transplantation, and atherosclerosis. To test our hypothesis that HO-1 regulates macrophage po...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Zhang, Min, Nakamura, Kojiro, Kageyama, Shoichi, Lawal, Akeem O., Gong, Ke Wei, Bhetraratana, May, Fujii, Takehiro, Sulaiman, Dawoud, Hirao, Hirofumi, Bolisetty, Subhashini, Kupiec-Weglinski, Jerzy W., Araujo, Jesus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237471/
https://ncbi.nlm.nih.gov/pubmed/30282830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.120596
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