Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice

Copeptin, a marker of arginine vasopressin (AVP) secretion, is elevated throughout human pregnancies complicated by preeclampsia (PE), and AVP infusion throughout gestation is sufficient to induce the major phenotypes of PE in mice. Thus, we hypothesized a role for AVP in the pathogenesis of PE. AVP...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Sandgren, Jeremy A., Deng, Guorui, Linggonegoro, Danny W., Scroggins, Sabrina M., Perschbacher, Katherine J., Nair, Anand R., Nishimura, Taryn E., Zhang, Shao Yang, Agbor, Larry N., Wu, Jing, Keen, Henry L., Naber, Meghan C., Pearson, Nicole A., Zimmerman, Kathy A., Weiss, Robert M., Bowdler, Noelle C., Usachev, Yuriy M., Santillan, Donna A., Potthoff, Matthew J., Pierce, Gary L., Gibson-Corley, Katherine N., Sigmund, Curt D., Santillan, Mark K., Grobe, Justin L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237463/
https://ncbi.nlm.nih.gov/pubmed/30282823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99403
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