Microbiota-sensitive epigenetic signature predicts inflammation in Crohn’s disease

Altered response to the intestinal microbiota strongly associates with inflammatory bowel disease (IBD); however, how commensal microbial cues are integrated by the host during the pathogenesis of IBD is not understood. Epigenetics represents a potential mechanism that could enable intestinal microb...

詳細記述

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書誌詳細
出版年:JCI Insight
主要な著者: Kelly, Daniel, Kotliar, Michael, Woo, Vivienne, Jagannathan, Sajjeev, Whitt, Jordan, Moncivaiz, Jessica, Aronow, Bruce J., Dubinsky, Marla C., Hyams, Jeffrey S., Markowitz, James F., Baldassano, Robert N., Stephens, Michael C., Walters, Thomas D., Kugathasan, Subra, Haberman, Yael, Sundaram, Nambirajan, Rosen, Michael J., Helmrath, Michael, Karns, Rebekah, Barski, Artem, Denson, Lee A., Alenghat, Theresa
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2018
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237229/
https://ncbi.nlm.nih.gov/pubmed/30232290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122104
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