Microbiota-sensitive epigenetic signature predicts inflammation in Crohn’s disease

Altered response to the intestinal microbiota strongly associates with inflammatory bowel disease (IBD); however, how commensal microbial cues are integrated by the host during the pathogenesis of IBD is not understood. Epigenetics represents a potential mechanism that could enable intestinal microb...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kelly, Daniel, Kotliar, Michael, Woo, Vivienne, Jagannathan, Sajjeev, Whitt, Jordan, Moncivaiz, Jessica, Aronow, Bruce J., Dubinsky, Marla C., Hyams, Jeffrey S., Markowitz, James F., Baldassano, Robert N., Stephens, Michael C., Walters, Thomas D., Kugathasan, Subra, Haberman, Yael, Sundaram, Nambirajan, Rosen, Michael J., Helmrath, Michael, Karns, Rebekah, Barski, Artem, Denson, Lee A., Alenghat, Theresa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237229/
https://ncbi.nlm.nih.gov/pubmed/30232290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122104
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