Laminin α1 is a genetic modifier of TGF-β1–stimulated pulmonary fibrosis

The pathogenetic mechanisms underlying the pathologic fibrosis in diseases such as idiopathic pulmonary fibrosis (IPF) are poorly understood. To identify genetic factors affecting susceptibility to IPF, we analyzed a murine genetic model of IPF in which a profibrotic cytokine (TGF-β1) was expressed...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lee, Chang-Min, Cho, Soo Jung, Cho, Won-Kyung, Park, Jin Wook, Lee, Jae-Hyun, Choi, Augustine M., Rosas, Ivan O., Zheng, Ming, Peltz, Gary, Lee, Chun Geun, Elias, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237225/
https://ncbi.nlm.nih.gov/pubmed/30232270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99574
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