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The phosphatidic acid phosphatase lipin-1 facilitates inflammation-driven colon carcinogenesis

Colon cancer is a devastating illness that is associated with gut inflammation. Here, we explored the possible role of lipin-1, a phosphatidic acid phosphatase, in the development of colitis-associated tumorigenesis. Azoxymethane and dextran sodium sulfate–treated (DSS-treated) animals deficient in...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Meana, Clara, García-Rostán, Ginesa, Peña, Lucía, Lordén, Gema, Cubero, África, Orduña, Antonio, Győrffy, Balázs, Balsinde, Jesús, Balboa, María A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237220/
https://ncbi.nlm.nih.gov/pubmed/30232275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.97506
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