Leukotriene B(4) promotes neovascularization and macrophage recruitment in murine wet-type AMD models

Age-related macular degeneration (AMD), a progressive chronic disease of the central retina, is associated with aging and is a leading cause of blindness worldwide. Here, we demonstrate that leukotriene B(4) (LTB(4)) receptor 1 (BLT1) promotes laser-induced choroidal neovascularization (CNV) in a mo...

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Enregistré dans:
Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Sasaki, Fumiyuki, Koga, Tomoaki, Ohba, Mai, Saeki, Kazuko, Okuno, Toshiaki, Ishikawa, Keijiro, Nakama, Takahito, Nakao, Shintaro, Yoshida, Shigeo, Ishibashi, Tatsuro, Ahmadieh, Hamid, Kanavi, Mozhgan Rezaei, Hafezi-Moghadam, Ali, Penninger, Josef M., Sonoda, Koh-Hei, Yokomizo, Takehiko
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2018
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237215/
https://ncbi.nlm.nih.gov/pubmed/30232269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.96902
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