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Highly diastereoselective synthesis of tricyclic fused-pyrans by sequential hydride shift mediated double C(sp(3))–H bond functionalization

Described herein is the Brønsted acid-catalyzed double C(sp(3))–H bond functionalization of alkyl phenethyl ether derivatives. In this process, a [1,5]-[1,5]-hydride shift occurred successively to afford tricyclic fused pyran derivatives in excellent chemical yields with excellent diastereoselectivi...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Mori, Keiji, Umehara, Nobuaki, Akiyama, Takahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237131/
https://ncbi.nlm.nih.gov/pubmed/30542535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02103a
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