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Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling

Pseudomonas aeruginosa infections have reached a “critical” threat status making novel therapeutic approaches required. Inhibiting key signaling enzymes known as the histidine kinases (HKs), which are heavily involved with its pathogenicity, has been postulated to be an effective new strategy for tr...

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Pubblicato in:Chem Sci
Autori principali: Goswami, Manibarsha, Espinasse, Adeline, Carlson, Erin E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237130/
https://ncbi.nlm.nih.gov/pubmed/30542536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02496k
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