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Disarming the virulence arsenal of Pseudomonas aeruginosa by blocking two-component system signaling

Pseudomonas aeruginosa infections have reached a “critical” threat status making novel therapeutic approaches required. Inhibiting key signaling enzymes known as the histidine kinases (HKs), which are heavily involved with its pathogenicity, has been postulated to be an effective new strategy for tr...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Goswami, Manibarsha, Espinasse, Adeline, Carlson, Erin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6237130/
https://ncbi.nlm.nih.gov/pubmed/30542536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02496k
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