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Synthesis of Acridine-based DNA Bis-intercalating Agents

Methods for the synthesis of N(1), N(8)-bis(9-acridinyl)-N(4)-(4-hydroxybenzyl)-spermidine and N(1), N(7)-(hydroxybenzyl)-bis-(3-aminopropyl)amine were investigated. Thus monocyanoethylation of 4-methoxybenzylamine followed by treatment with 4-chlorobutyronitrile gave the dinitrile N-(2-cyanoethyl)-...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Moloney, Gerard P., Kelly, David P., Mack, P.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236396/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/60300230
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