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Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway

Acute kidney injury (AKI) is a clinically common and severe complication of ischemia-reperfusion (I/R), associated with high morbidity and mortality rates, and prolonged hospitalization. Rapamycin is a type of macrolide, primarily used for anti-rejection therapy following organ transplantation and t...

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Foilsithe in:Mol Med Rep
Main Authors: Su, Yang, Lu, Jingxiao, Gong, Pian, Chen, Xianguo, Liang, Chaozhao, Zhang, Jie
Formáid: Artigo
Teanga:Inglês
Foilsithe: D.A. Spandidos 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6236225/
https://ncbi.nlm.nih.gov/pubmed/30365078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.9586
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