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Making CAR T Cells a Solid Option for Solid Tumors

Adoptive cell therapy with chimeric antigen receptor (CAR) T cells aims to redirect the patient's own immune system to selectively attack cancer cells. To do so, CAR T cells are endowed with specific antigen recognition moieties fused to signaling and costimulatory domains. While this approach...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Schmidts, Andrea, Maus, Marcela V.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235951/
https://ncbi.nlm.nih.gov/pubmed/30467505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02593
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