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21-Gene assay as predictor of chemotherapy benefit in HER2-negative breast cancer

The NSABP B-20 prospective-retrospective study of the 21-gene Oncotype DX Breast Cancer Recurrence Score® test predicted benefit from addition of chemotherapy to tamoxifen in node-negative, estrogen-receptor positive breast cancer when recurrence score (RS) was ≥31. HER2 is a component of the RS alg...

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Bibliografske podrobnosti
izdano v:NPJ Breast Cancer
Main Authors: Geyer, Charles E., Tang, Gong, Mamounas, Eleftherios P., Rastogi, Priya, Paik, Soonmyung, Shak, Steven, Baehner, Frederick L., Crager, Michael, Wickerham, D. Lawrence, Costantino, Joseph P., Wolmark, Norman
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235896/
https://ncbi.nlm.nih.gov/pubmed/30456299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-018-0090-6
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